Inhaltsbereich
Institut für Genetische Epidemiologie
2017
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Gorski, M.;
van der Most, P.J.;
Teumer, A.;
Chu, A.Y.;
Li, M.;
Mijatovic, V.;
Nolte, I.M.;
Cocca, M.;
Taliun, D.;
Gomez, F.;
Li, Y.;
Tayo, B.;
Tin, A.;
Feitosa, M.F.;
Aspelund, T.;
Attia, J.;
Biffar, R.;
Gieger, C.;
Meisinger, C.;
Meitinger, T.;
Strauch, K.;
Waldenberger, M.;
Fuchsberger, C.
(2017)
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function
erschienen in: Sci Rep 7:45040, 1-10 (2017)
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Liu, C.;
Marioni, R.E.;
Hedman, A.;
Pfeiffer, L.;
Tsai, P.C.;
Reynolds, L.;
Just, A.C.;
Duan, Q.;
Boer, C.G.;
Tanaka, T.;
Elks, C.E.;
Aslibekyan, S.;
Brody, J.A.;
Kühnel, B.;
Herder, C.;
Liang, L.;
Kretschmer, A.;
Strauch, K.;
Peters, A.;
Waldenberger, M.;
Levy, D.
(2017)
A DNA Methylation Biomarker of Alcohol Consumption
erschienen in: Mol Psychiatry, Stand 11/2016: Online first
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Mack, S.;
Coassin, S.;
Rueedi, R.;
Yousri, N.A.;
Seppälä, I.;
Gieger, C.;
Schönherr, S.;
Forer, L.;
Erhart, G.;
Marques-Vidal, P.;
Ried, J.S.;
Waeber, G.;
Bergmann, S.;
Dähnhardt, D.;
Stöckl, A.;
Raitakari, O.T.;
Kähönen, M.;
Peters, A.;
Meitinger, T.;
Strauch, K.;
KORA study group;
Kronenberg, F.
(2017)
A genome-wide association meta-analysis on lipoprotein(a) concentrations adjusted for apolipoprotein(a) isoforms
erschienen in: J Lipid Res 58, 1834-1844 (2017)
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Manning, A.K.;
Highland, H.M.;
Gasser, J.;
Hrabé de Angelis, M.;
Schwarzmayr, T.;
Strom, T.M.;
Wieland, T.;
Thorand, B.;
Strauch, K.;
Peters, A.;
Müller-Nurasyid, M.;
Kriebel, J.;
Illig, T.;
Grallert, H.;
Gieger, C.;
Meisinger, C.;
Meitinger, T.
(2017)
A low-frequency inactivating AKT2 variant enriched in the Finnish population is associated with fasting insulin levels and type 2 diabetes risk
erschienen in: Diabetes 66, 2019-2032 (2017)
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Scott, R.A.;
Scott, L.J.;
Mägi, R.;
Marullo, L.;
Gaulton, K.J.;
Kaakinen, M.;
Pervjakova, N.;
Pers, T.H.;
Johnson, A.D.;
Eichler, J.D.;
Jackson, A.U.;
Grallert, H.;
Müller-Nurasyid, M.;
Meitinger, T.;
Thorand, B.;
Klopp, N.;
Meyer, J.;
Gieger, C.;
Strauch, K.;
Prokopenko, I.
(2017)
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
erschienen in: Diabetes, Stand 6/2017: Online first
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Coassin, S.;
Erhart, G.;
Weissensteiner, H.;
Guimareas de Araujo, M.E.;
Lamina, C.;
Schönherr, S.;
Forer, L.;
Haun, M.;
Losso, J.L.;
Köttgen, A.;
Schmidt, K.;
Utermann, G.;
Peters, A.;
Gieger, C.;
Strauch, K.;
Finkenstedt, A.;
Bale, R.;
Zoller, H.;
Paulweber, B.;
Eckart, K.U.;
Hüttenhofer, A.;
Huber, L.A.;
Kronenberg, F.
(2017)
A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction
erschienen in: Eur Heart J, Stand 5/2017: Online first
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Emeny, R.;
Baumert, J.;
Zannas, A.;
Kunze, S.;
Wahl, S.;
Iurato, S.;
Arloth, J.;
Erhardt, A.;
Balsevich, G.;
Schmidt, M.V.;
Weber, P.;
Kretschmer, A.;
Pfeiffer, L.;
Kruse, J.;
Strauch, K.;
Roden, M.;
Herder, C.;
Koenig, W.;
Gieger, C.;
Waldenberger, M.;
Peters, A.;
Binder, E.B.;
Ladwig, K.H.
(2017)
Anxiety Associated Increased CpG Methylation in the Promoter of ASB1: A translational approach evidenced by epidemiological and clinical studies and a murine model
erschienen in: Neuropsychopharmacology, Stand 5/2017: Online first
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Standl, M.;
Tesch, F.;
Baurecht, H.;
Rodriguez, E.;
Müller-Nurasyid, M.;
Gieger, C.;
Peters, A.;
Wang-Sattler, R.;
Prehn, C.;
Adamski, J.;
Kronenberg, F.;
Schulz, H.;
Koletzko, S.;
Schikowski, T.;
von Berg, A.;
Lehmann, I.;
Berdel, D.;
Heinrich, J.;
Weidinger, S.
(2017)
Association of atopic dermatitis with cardiovascular risk factors and diseases
erschienen in: JID 137, 1074-1081 (2017)
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Suhre, K.;
Arnold, M.;
Bhagwat, A.M.;
Cotton, R.J.;
Engelke, R.;
Raffler, J.;
Sarwath, H.;
Thareja, G.;
Wahl, A.;
DeLisle, R.K.;
Gold, L.;
Pezer, M.;
Lauc, G.;
El-Din Selim, M.A.;
Mook-Kanamori, D.O.;
Al-Dous, E.K.;
Mohamoud, Y.A.;
Strauch, K.;
Grallert, H.;
Peters, A.;
Gieger, C.;
Graumann, J.
(2017)
Connecting genetic risk to disease end points through the human blood plasma proteome
erschienen in: Nat Comm 8:14357, 1-13 (2017)
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van den Berg, M.E.;
Warren, H.R.;
Cabrera, C.P.;
Verweij, N.;
Mifsud, B.;
Haessler, L.;
Bihlmeyer, N.A.;
Fu, Y.P.;
Weiss, S.;
Lin, H.J.;
Grarup, N.;
Li-Gao, R.;
Pistis, G.;
Shah, N.;
Brody, J.A.;
Müller-Nurasyid, M.;
Lin, H.;
Mei, H.;
Smith, A.V.;
Lyytikäinen, L.P.;
Hall, L.M.;
van Setten, J.;
Peters, A.;
Waldenberger, M.;
Munroe, P.B.
(2017)
Discovery of novel heart rate-associated loci using the Exome Chip
erschienen in: Hum Mol Genet 26(12), 2346-2363 (2017)
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Wahl, S.;
Drong, A.;
Lehne, B.;
Loh, M.;
Scott, W.R.;
Kunze, S.;
Tsai, P.C.;
Ried, J.S.;
Kriebel, J.;
Meisinger, C.;
Meitinger, T.;
Strauch, K.;
Thorand, B.;
Peters, A.;
Illig, T.;
Waldenberger, M.;
Gieger, C.;
Grallert, H.;
Chambers, J.C.
(2017)
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
erschienen in: Nature 541, 81-86 (2017) (Letter)
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Esslinger, U.;
Garnier, S.;
Korniat, A.;
Proust, C.;
Kararigas, G.;
Müller-Nurasyid, M.;
Empana, J.P.;
Morley, M.P.;
Perret, C.;
Stark, K.;
Bick, A.G.;
Prasad, S.K.;
Kriebel, J.;
Li, J.;
Tiret, L.;
Strauch, K.;
O'Regan, D.P.;
Marguiles, K.B.;
Seidman, J.G.;
Boutouyrie, P.;
Lacolley, P.;
Jouven, X.;
Grallert, H.;
Villard, E.
(2017)
Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy
erschienen in: PLoS One 12(3):e0172995, 1-16 (2017)
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Nolte, I.M.;
Munoz, M.L.;
Tragante, V.;
Amare, A.T.;
Jansen, R.;
Vaez, A.;
von der Heyde, B.;
Avery, C.L.;
Bis, J.C.;
Dierckx, B.;
van Dongen, J.;
Gogarten, S.M.;
Goyette, P.;
Hernesniemi, J.;
Huikari, V.;
Hwang, S.J.;
Jaju, D.;
Müller-Nurasyid, M.;
Perz, S.;
Peters, A.;
Strauch, K.;
Waldenberger, M.;
de Geus, E.J.C.
(2017)
Genetic loci associated with heart rate variability and their effects on cardiac disease risk
erschienen in: Nat Com 8:15805, 1-15 (2017)
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Jäger, S.;
Wahl, S.;
Kröger, J.;
Sharma, S.;
Hoffmann, P.;
Floegel, A.;
Pischon, T.;
Prehn, C.;
Adamski, J.;
Müller-Nurasyid, M.;
Waldenberger, M.;
Strauch, K.;
Peters, A.;
Gieger, C.;
Suhre, K.;
Grallert, H.
(2017)
Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes
erschienen in: Sci Rep 7:6037, 1-12 (2017)
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Ellinghaus, D.;
Ellinghaus, E.;
Krusche, P.;
Greiner, A.;
Schreiber, C.;
Nikolaus, S.;
Gieger, C.;
Strauch, K.;
Lieb, W.;
Rosenstiel, P.;
Frings, N.;
Fiebig, A.;
Schreiber, S.;
Franke, A.
(2017)
Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci
erschienen in: Sci Rep 7:45652, 1-9 (2017)
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Rosendahl, J.;
Kirsten, H.;
Heghi, E.;
Kovacs, P.;
Weiss, F.U.;
Laumen, H.;
Lichtner, P.;
Ruffert, C.;
Chen, J.M.;
Masson, E.;
Beer, S.;
Zimmer, C.;
Seltsam, K.;
Algül, H.;
Bühler, F.;
Bruno, M.J.;
Bugert, P.;
Burgkhardt, R.;
Cavestro, G.M.;
Cichoz-Lach, H.;
Farré, A.;
Grallert, H.;
Peters, A.;
Strauch, K.;
Sahin-Tóth, M.;
all members of the PanEuropean Working group on ACP
(2017)
Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis
erschienen in: Gut, Stand 9/2017: Online first
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Rahmani, E.;
Shenhav, L.;
Schweiger, R.;
Yousefi, P.;
Huen, K.;
Eskenazi, B.;
Eng, C.;
Huntsman, S.;
Hu, D.;
Galanter, J.;
Oh, S.;
Waldenberger, M.;
Strauch, K.;
Grallert, H.;
Meitinger, T.;
Gieger, C.;
Holland, N.;
Burchard, E.;
Zaitlen, N.;
Halperin, E.
(2017)
Genome-wide methylation data mirror ancestry information
erschienen in: Epigenetics Chromatin 10:1, 1-12 (2017)
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Graff, M.;
Scott, R.A.;
Justice, A.E.;
Young, K.L.;
Feitosa, M.F.;
Barata, L.;
Winkler, T.W.;
Chu, A.Y.;
Mahajan, A.;
Gieger, C.;
Grallert, H.;
Holzapfel, C.;
Huth, C.;
Müller-Nurasyid, M.;
Peters, A.;
Rawal, R.;
Thorand, B.;
Strauch, K.;
Kilpeläinen, T.O.
(2017)
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200, 452 adults
erschienen in: PLoS Genet 13(4):e1006528, 1-26 (2017)
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Day, F.R.;
Thompson, D.J.;
Helgason, H.;
Chasman, D.I.;
Finucane, H.;
Sulem, P.;
Ruth, K.S.;
Whalen, S.;
Sarkar, A.K.;
Albrecht, E.;
Altmaier, E.;
Grallert, H.;
Meisinger, C.;
Meitinger, T.;
Peters, A.;
Strauch, K.;
Gieger, C.;
Stöckl, D.;
Perry, J.R.B.
(2017)
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
erschienen in: Nat Genet 49(6), 834-841 (2017)
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Schellnegger, R.;
Quante, A.;
Rospleszcz, S.;
Schernhammer, M.;
Höhl, B.;
Tobiasch, M.;
Pastula, A.;
Brandtner, A.;
Abrams, J.A.;
Strauch, K.;
Schmid, R.M.;
Vieht, M.;
Wang, T.C.;
Quante, A.
(2017)
Goblet-cell ratio in combination with differentiation and stem cell markers in Barrett's esophagus allow distinction of patients with and without EAC
erschienen in: Cancer Prev Res 10(1), 55-66 (2017)
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Skaaby, T.;
Taylor, A.E.;
Jakobsen, R.K.;
Paternoster, L.;
Thuesen, B.H.;
Ahluwalia, T.S.;
Larsen, S.C.;
Zhou, A.;
Wong, A.;
Gabrielsen, M.E.;
Bjorngaard, J.H.;
Flexeder, C.;
Männistö, S.;
Hardy, R.;
Kuh, D.;
Barry, S.J.E.;
Mollehave, L.T.;
Cerqueira, C.;
Schulz, H.;
Strauch, K.;
Meitinger, T.;
Peters, A.;
Grallert, H.;
Linneberg, A.
(2017)
Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium
erschienen in: Sci Rep 7:2224, 1-9 (2017)
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Christophersen, I.E.;
Rienstra, M.;
Roselli, C.;
Yin, X.;
Geelhoed, B.;
Barnard, J.;
Lin, H.;
Arking, D.E.;
Smith, A.V.;
Albert, C.M.;
Chaffin, M.;
Tucker, N.R.;
Li, M.;
Klarin, D.;
Bihlmeyer, N.A.;
Müller-Nurasyid, M.;
Perz, S.;
Waldenberger, M.;
Lichtner, P.;
Peters, A.;
Kriebel, J.;
Ellinor, P.T.;
the AFGen Consortium
(2017)
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
erschienen in: Nat Genet 49(6), 946-952 (2017)
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Kowall, B.;
Rathmann, W.;
Stang, A.;
Bongaerts, B.;
Kuss, O.;
Herder, C.;
Roden, M.;
Quante, A.;
Holle, R.;
Huth, C.;
Peters, A.;
Meisinger, C.
(2017)
Perceived risk of diabetes seriously underestimates actual diabetes risk: The KORA FF4 study
erschienen in: PLoS One 12(1):e0171152, 1-13 (2017)
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Jegan, N.R.A.;
Brugger, M.;
Viniol, A.;
Strauch, K.;
Barth, J.;
Baum, E.;
Leonhardt, C.;
Becker, A.
(2017)
Psychological risk and protective factors for disability in chronic low back pain - a longitudinal analysis in primary care
erschienen in: BMC Musculoskeletal Disorders 18:114, 1-11 (2017)
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CKDGen Consortium;
Li, M.;
Li, Y.;
Weeks, O.;
Mijatovic, V.;
Teumer, A.;
Huffman, A.;
Tromp, G.;
Fuchsberger, C.;
Gorski, M.;
Lyytikäinen, L.P.;
Nutile, T.;
Sedaghat, S.;
Sorice, R.;
Tin, A.;
Yang, Q.;
Ahluwalia, T.S.;
Arking, D.E.;
Kriebel, J.;
Meisinger, C.;
Peters, A.;
Strauch, K.;
Waldenberger, M.;
Chu, A.Y.
(2017)
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function
erschienen in: J Am Soc Nephrol 28, 981-994 (2017)
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Webb, T.R.;
Erdmann, J.;
Stirrups, K.E.;
Stiziel, N.O.;
Masca, N.G.D.;
Jansen, H.;
Kanoni, S.;
Nelson, C.P.;
Ferrario, P.G.;
König, I.R.;
Eicher, J.D.;
Kriebel, J.;
Meisinger, C.;
Müller-Nurasyid, M.;
Strauch, K.;
Waldenberger, M.;
Meitinger, T.;
Peters, A.;
Kathiresan, S.
(2017)
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
erschienen in: J Am Coll Cardiol 69(7), 823-836 (2017)
2016
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van der Harst, P.;
van Setten, J.;
Verweij, N.;
Vogler, G.;
Franke, L.;
Maurano, M.T.;
Wang, X.;
Leach, I.M.;
Eijgelsheim, M.;
Sotoodehnia, N.;
Hayward, C.;
Sorice, R.;
Meirelles, O.;
Müller-Nurasyid, M.;
Gieger, C.;
Meitinger, T.;
Perz, S.;
Peters, A.;
Strauch, K.;
Waldenberger, M.;
de Bakker, P.I.W.
(2016)
52 Genetic Loci Influencing Myocardial Mass
erschienen in: J Am Coll Cardiology 68(13), 1435-1448 (2016)
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Lamina, C.;
Friedel, S.;
Coassin, S.;
Rueedi, R.;
Yousri, N.A.;
Seppälä, I.;
Gieger, C.;
Schönherr, S.;
Forer, L.;
Erhart, G.;
Kollerits, B.;
Marques-Vidal, P.;
Ried, J.;
Waeber, G.;
Bergmann, S.;
Dähnhardt, D.;
Stöckl, A.;
Peters, A.;
Strauch, K.;
KORA study group;
Kronenberg, F.
(2016)
A Genome-wide Association Meta-analysis on Apolipoprotein A-IV Concentrations
erschienen in: HMG 25(16), 3635-3646 (2016)
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de Vries, P.S.;
Chasman, D.I.;
Sabater-Lleal, M.;
Chen, M.H.;
Huffman, J.E.;
Steri, M.;
Tang, W.;
Teumer, A.;
Marioni, R.E.;
Grossmann, V.;
Hottenga, J.J.;
Trompet, S.;
Müller-Nurasyid, M.;
Zhao, W.;
Brody, J.A.;
Kleber, M.E.;
Guo, X.;
Wang, J.J.;
Auer, P.L.;
Riess, H.;
Waldenberger, M.;
Peters, A.;
Dehghan, A.
(2016)
A meta-analysis of 120, 246 individuals identifies 18 new loci for fibrinogen concentration
erschienen in: Hum Mol Genet 25(2), 358-370 (2016)
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Kanoni, S.;
Masca, N.G.D.;
Stirrups, K.E.;
Varga, T.V.;
Warren, H.R.;
Scott, R.A.;
Southam, L.;
Zhang, W.;
Yoghootkar, H.;
Müller-Nurasyid, M.;
Couto Alves, A.;
Strawbridge, R.J.;
Lataniotis, L.;
Hashim, N.A.A.;
Besse, C.;
Boland, A.;
Grallert, H.;
Peters, A.;
Strauch, K.;
Waldenberger, M.;
Gieger, C.;
Deloukas, P.
(2016)
Analysis with the exome array identifies multiple new independent variants in lipid loci
erschienen in: Hum Mol Genet 25(18), 4094-4106 (2017)
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Ried, J.S.;
Jeff, J.M.;
Chu, A.Y.;
Bragg-Gresham, J.L.;
van Dongen, J.;
Huffman, J.E.;
Ahluwalia, T.S.;
Cadby, G.;
Eklund, N.;
Erksson, J.;
Esko, T.;
Feitosa, M.F.;
Goel, A.;
Gorski, M.;
Hayward, C.;
Heard-Costa, N.L.;
Jackson, A.U.;
Albrecht, E.;
Grallert, H.;
Strauch, K.;
Gieger, C.;
Peters, A.;
Müller-Nurasyid, M.;
Loos, R.J.S.
(2016)
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
erschienen in: Nat Commun 7:13357, 1-11 (2016)
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Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators;
Stiziel, N.O.;
Stirrups, K.E.;
Masca, N.G.D.;
Erdmann, J.;
Ferrario, P.G.;
König, I.R.;
Weeke, P.E.;
Webb, T.R.;
Auer, P.L.;
Schick, U.M.;
Lu, Y.;
Zhang, W.;
Dube, M.P.;
Goel, A.;
Kriebel, J.;
Meisinger, C.;
Müller-Nurasyid, M.;
Strauch, K.;
Waldenberger, M.;
Peters, A.;
Schunkert, H.
(2016)
Coding Variation in ANGTL4, LPL, and SVEP1 and the Risk of Coronary Disease
erschienen in: New Engl J Med 374(12), 1134-1144 (2016)
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Baurecht, H.;
Hotze, M.;
Rodriguez, E.;
Manz, J.;
Weidinger, S.;
Cordell, H.J.;
Augustin, T.;
Strauch, K.
(2016)
Compare and Contrast Meta Analysis (CCMA): A Method for Identification of Pleiotropic Loci in Genome-Wide Association Studies
erschienen in: PLoS One 11(5):e0154872, 1-10 (2016)
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Nowak, C.;
Salihovic, S.;
Ganna, A.;
Brandmaier, S.;
Tukiainen, T.;
Broeckling, C.D.;
Magnusson, P.K.;
Prenni, J.E.;
Wang-Sattler, R.;
Peters, A.;
Strauch, K.;
Meitinger, T.;
Giedraitis, V.;
Ärnlöy, J.;
Berne, C.;
Gieger, C.;
Ripatti, S.;
Lind, L.;
Pedersen, N.L.;
Sundström, J.;
Ingelsson, E.;
Fall, T.
(2016)
Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study
erschienen in: PLoS Genet 12(10):e1006379, 1-19 (2016)
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Marzi, C.;
Holdt, L.M.;
Fiorito, G.;
Tsai, P.C.;
Kretschmer, A.;
Wahl, S.;
Guarrera, S.;
Teupser, D.;
Spector, T.D.;
Iacoviello, L.;
Sacerdote, C.;
Strauch, K.;
Peters, A.;
Thorand, B.;
Gieger, C.;
Waldenberger, M.;
Grallert, H.;
Koenig, W.
(2016)
Epigenetic signatures at AQP3 and SOCS3 engage in low-grade inflammation across different tissues
erschienen in: PLoS One 11(11):e0166015, 1-14 (2016)
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Pattaro, C.;
Teumer, A.;
Gorski, M.;
Chu, A.Y.;
Li, M.;
Mijatovic, V.;
Garnaas, M.;
Tin, A.;
Sorice, R.;
Li, Y.;
Taliun, D.;
Olden, M.;
Foster, M.;
Yang, Q.;
Chen, M.H.;
Gieger, C.;
Grallert, H.;
Wichmann, H.E.;
Heid, I.M.;
Meisinger, C.;
Illig, T.;
Fox, C.S.
(2016)
Genetic association at 53 loci highlight cell types and biological pathways relevant for kidney function
erschienen in: Nat Communications 7:10023, 1-19 (2016)
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Okbay, A.;
Baselmans, B.M.L.;
De Neve, J.E.;
Turley, P.;
Nivard, M.G.;
Fontana, M.A.;
Meddens, S.F.W.;
Linnér, R.K.;
Rietveld, C.A.;
Derringer, J.;
Gratten, J.;
Lee, J.J.;
de Vlaming, R.;
Ahluwalia, T.S.;
Buchwald, J.;
Cavadina, A.;
Franzier-Wood, A.C.;
Furlotte, N.A.;
Ladwig, K.H.;
Rawal, R.;
Emeny, R.T.;
Gieger, C.;
Cesarini, D.
(2016)
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
erschienen in: Nat Genet 48(6), 624-633 (2016)
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Marioni, R.E.;
Ritchie, S.J.;
Joshi, P.K.;
Hagenaars, S.P.;
Okbay, A.;
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Genome-wide analysis identifies 12 loci influencing human reproductive behavior
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Genome-Wide Analysis of DNA Methylation and Fine Particulate Matter Air Pollution in Three Study Populations: KORA F3, KORA F4, and the Normative Aging Study
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Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study
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Projections of Cancer Incidence and Cancer-related Deaths in Germany to 2020 and 2030
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Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
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Mitochondrial genetic variants identified to be associated with posttraumatic stress disorder
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Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans
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Shungin D;
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Strawbridge RJ;
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Fischer K;
Albrecht E;
Grallert H;
Müller-Nurasyid M;
Ried J;
The CARDIOGRAMplusC4D Consortium;
The MAGIC Investigators;
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Illig T;
Peters A;
Strauch K;
Wichmann HE;
Heid IM;
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New genetic loci link adipose and insulin biology to body fat distribution
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Shungin D;
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Pers TH;
Fischer K;
Albrecht E;
Grallert H;
Müller-Nurasyid M;
Ried J;
The CARDIOGRAMplusC4D Consortium;
The MAGIC Investigators;
Gieger C;
Illig T;
Peters A;
Strauch K;
Wichmann HE;
Heid IM;
Mohlke KL
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New genetic loci link adipose and insulin biology to body fat distribution
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Ried JS
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Nonadditive Effects of Genes in Human Metabolomics
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Segrè AV;
Wei N;
DIAGRAM Consortium (with Grallert H, Müller-Nurasyid M, Klopp N, Thorand B, Gieger C, Peters A, Illig T et al.);
MAGIC investigators (with Grallert H, Gieger C, Meisinger C, Thorand B, Wichmann HE et al);
Altshuler D;
Florez JC
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Pathways targeted by anti-diabetes drugs are enriched for multiple genes associated with type 2 diabetes risk
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Quante A;
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Practical problems with clinical guidelines for breast cancer prevention based on remaining lifetime risk
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the German Competence Network for Multiple Sclerosis
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Sucessful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array
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Bartel, J. ;
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The Human Blood Metabolome-Transcriptome Interface
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The impact of low-frequency and rare variants on lipid levels
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Reinthaler EM;
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16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy
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Meder B;
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A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy
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Chan Y;
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McKnight AJ;
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DIAGRAM Consortium (with Grallert H, Müller-Nurasyid M, Klopp NB, Thorand B, Gieger C, Peters A, Illig T et al.);
GENIE Consortium;
GIANT Consortium;
IIBDGC Consortium;
PGC Consortium;
Daly MJ;
Neale BM;
Salem RM;
Hirschhorn JN
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An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases
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Assessing the goodness of fit of personal risk models
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Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11, 448 participants
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LifeLines Cohort Study;
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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomization study
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Associations between thyroid hormones and serum metabolite profiles in an euthyroid population
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Association study of mitochondrial genetic polymorphisms in asthmatic children
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A Systematic Evaluation of Short Tandem Repeats in Lipid Candidate Genes: Riding on the SNP-Wave
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Changes in mammographic density over time in breast cancer cases and women at high risk for breast cancer
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Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest
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Lusis AJ;
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Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine
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Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R
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Cord blood LC-PUFA composition and allergic diseases during the first 10 years. Results from the LISAplus study
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Defining the role of common variation in the genomic and biological architecture of adult human height
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Defining the role of common variation in the genomic and biological architecture of adult human height
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Effects of air pollution on exhaled nitric oxide in children: Results from the GINIplus and LISAplus studies
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Hwang SJ;
Papanicolau GJ;
Sijbrands EJ;
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Eiriksdottir G;
Global Blood Pressure Genetics Consortium (with Döring A, Gieger C, Illig T, Wichmann HE et al.);
Chakravarti A
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Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic Associations
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Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits
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Small KS;
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MAGIC Consortium (with Grallert HH, Gieger C, Thorand B, Meisinger C, Illig T, Wichmann HE et al.);
DIAGRAM Consortium (with Grallert H, Müller-Nurasyid M, Klopp NB, Thorand B, Gieger C, Peters A, Illig T et al.);
Hanson O
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Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated with Insulin Sensitivity
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Fast Linkage Analysis with MOD Scores Using Algebraic Calculation
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Almoguera B;
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Farrall M;
Fischer ME;
Gaunt TR;
Gho JMIH;
Gieger C;
Thorand B;
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Keating BJ
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Gene-centric Meta-analysis in 87, 736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci
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Müller-Nurasyid M;
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
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Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits
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International League Against Epilepsy Consortium on Complex Epilepsies (with Peters A, Heinrich J, Holle R, Leidl R, Meisinger C, Strauch K, Gieger C, Grallert HH et al.)
(2014)
Genetic determinants of common epilepsies: A meta-analysis of genome-wide association studies
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Hinney A;
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Chapman J;
Harold D;
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Scherag A;
Wiltfang J;
Williams J;
Hebebrand J;
GERAD Consortium;
IGAP Consortium;
GIANT Consortium (with Albrecht E, Müller-Nurasyid M, Peters A, Thorand B, Gieger C, Illig T, Wichmann HE et al.)
(2014)
Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity
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Lüneburg N;
Lieb W;
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Chen MH;
Maas R;
Carter AM;
Xanthakis V;
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Schwedhelm E;
Seshadri S;
Ikram MA;
Longstreth W;
Fornage M;
König IR;
Nahrstaedt J;
Ojeda-Echevarria F;
Schillert A;
Wang TJ;
Gieger C;
Illig T;
Meisinger C;
Wichmann HE;
Böger RH
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Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine
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Simpson CL;
Wojciechowski R;
Oexle K;
Murgia F;
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Verhoeven VJM;
Vitart V;
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Hosseini SM;
Hysi PG;
Raffel LJ;
Cotch MF;
Chew E;
Klein BEK;
Klein R;
Wong TY;
van Duijn CM;
Mitchell P;
Saw SM;
Fossarello M;
Döring A;
Gieger C;
Wichmann HE;
Stambolian DD
(2014)
Genome-wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Evidence for Replication of 11 Loci
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DIAGRAM Consortium;
AGEN-T2D Consortium;
SAT2D Consortium;
MAT2D Consortium;
T2D-GENES Consortium;
Mahajan A;
Gieger C;
Grallert H;
Illig T;
Klopp N;
Müller-Nurasyid M;
Peters A;
Morris AP
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
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MacIntyre EA;
Brauer M;
Melén E;
Bauer CP;
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Brunekreef B;
Chan-Yeung M;
Klümper C;
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Gehring U;
Gref A;
Heinrich J;
Herbarth O;
Kerkhof M;
Koppelman GH;
Kozyrskyj AL;
Pershagen G;
Postma DS;
Thiering E;
Tiesler CMT;
Carlsten C;
for the TAG Study Group
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GSTP1 and TNF Gene Variants and Associations between Air Pollution and Incident Childhood Asthma: The Traffic, Asthma and Genetics (TAG) Study
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Gorski M;
Winkler TW;
Stark K;
Müller-Nurasyid M;
Ried JS;
Grallert H;
Weber BHF;
Heid IM
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Harmonization of Study and Reference Data by PhaseLift: Saving Time When Imputing Study Data
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Kohlboeck G;
Romanos M;
Teuner CM;
Holle R;
Tiesler CMT;
Hoffmann B;
Schaaf B;
Lehmann I;
Herbarth O;
Koletzko S;
Bauer CP;
von Berg A;
Berdel D;
Heinrich H
(2014)
Healthcare use and costs associated with children's behavior problems
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Medici M;
Porcu E;
Pistis G;
Teumer A;
Brown SJ;
Jensen RA;
Rawal R;
Roef GL;
Plantinga TS;
Vermeulen SH;
Lahti J;
Simmonds MJ;
Husemoen LLN ;
Freathy RM;
Shields BM;
Gieger C;
Heier M;
Reischl E;
Wichmann HE;
Meisinger C;
Peeters RP
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Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease
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Sinner MF;
Tucker NR;
Lunetta KL;
Ozaki K;
Smith JG;
Trompet S;
Bis JC;
Lin H;
Chung MK;
Nielsen JB;
Lubitz SA;
Krijthe BP;
Magnani JW;
Ye J;
Gollob MH;
Tsunoda T;
Müller-Nurasyid M;
Lichtner P;
Peters A;
Dolmatova E;
Kubo M;
Smith JD;
Psaty BM;
Ellinor PT
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Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation
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Claussnitzer M;
Dankel SN;
Klocke B;
Grallert H;
Glunk V;
Berulava T;
Lee H;
Oskolkov N;
Fadista J;
Ehlers K;
Wahl S;
Hoffmann C;
Qian K;
Riess H;
Müller-Nurasyid M;
DIAGRAM+Consortium (with Huth C, Aulchenko YS, Grallert H, Gieger C, Petersen AK, Thorand B, Wichmann HE et al.);
Laumen H
(2014)
Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms
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Laschkolnig A;
Kollerits B;
Lamina C;
Meisinger C;
Rantner B;
Stadler M;
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African Ancestry Anthropometry Genetics Concortium;
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Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses
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Global Bpgen Consortium (with Eyheramendi S, Döring A et al.);
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Pleiotropic genes for metabolic syndrome and inflammation
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NHGRI JHS/FHS Allelic Spectrum Project;
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Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
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Simulation of Finnish Population History, Guided by Empirical Genetic Data, to Assess Power of Rare-Variant Tests in Finland
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Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk
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A Regulatory Variant in CCR6 Is Associated With Susceptibility to Antitopoisomerase-Positive Systemic Sclerosis
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Body mass index trajectory classes and incident asthma in childhood: Results from 8 European Birth Cohorts – a Global Allergy and Asthma European Network initiative
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Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL
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Genetic predisposition to higher blood pressure increases coronary artery disease risk
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Genome-Wide Association Study Pinpoints a New Functional ApoB Variant Influencing Oxidized LDL Levels and Cardiovascular Events
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GWAS of 126, 559 Individuals Identifies Genetic Variants Associated with Educational Attainment
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Interactions of Genetic and Environmental Risk Factors with Respect to Body Fat Mass in Children: Results from the ALSPAC Study
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Sex-stratified Genome-wide Association Studies Including 270, 000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
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Rivadeneira F;
C't Hoen PA;
Reinmaa E;
Fischer K;
Nelis M;
Grallert H;
Strauch K;
Franke L
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Systematic identification of trans eQTLs as putative drivers of known disease associations
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Fall T;
Hägg S;
Mägi R;
Ploner A;
Fischer K;
Horikoshi M;
Sarin AP;
Thorleifsson G;
Ladenvall C;
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Draisma H;
Ried JS;
van Zuydam NR;
Huikari V;
Illig T;
Gieger C;
Peters A;
Wichmann HE;
Prokopenko I;
for the ENGAGE consortium
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The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
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Zeilinger S;
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Klopp N;
Baurecht H;
Kleinschmidt A;
Gieger C;
Weidinger S;
Lattka E;
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Waldenberger M;
Illig T
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Tobacco smoking leads to extensive genome-wide changes in DNA methylation
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2012
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Flaquer A;
Strauch K
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A comparison of different linkage statistics in small to moderate sized pedigrees with complex diseases
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Hampel R;
Breitner S;
Schneider A;
Zareba W;
Kraus U;
Cyrys J;
Geruschkat U;
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Müller M;
Wichmann HE;
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for the Cooperative Health Research in the Region of Augsburg (KORA), Study Group
(2012)
Acute air pollution effects on heart rate variability are modified by SNPs involved in cardiac rhythm in individuals with diabetes or impaired glucose tolerance
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Bradfield JP;
Taal HR;
Timpson NJ;
Scherag A;
Lecoeur C;
Warrington N;
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Holst C;
Valcarel B;
Thiering E;
Salem RM;
Schumacher F;
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Sleiman PMA;
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Berkowitz RI;
Vimaleswaran KS;
Jarick I;
Pennell CE;
Evans DM;
St. Pourcain B;
Berry DJ;
Mook-Kanamori DO;
Hofman A;
Heinrich J;
Grant SFA;
for the Early Growth Genetics Consortium
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A genome-wide association meta-analysis identifies new childhood obesity loci
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Kääb S;
Crawford DC;
Sinner MF;
Behr ER;
Kannankeril PJ;
Wilde AAM;
Bezzina CR;
Schulze-Bahr E;
Guicheney P;
Bishopric;
Myerburg R;
Schott JJ;
Pfeufer A;
Beckmann BM;
Martens E;
Zhang T;
Stallmeyer B;
Zumhabgen S;
Denjoy I;
Bardai A;
Van Gelder IC;
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Dalageorgou C;
Marshall V;
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Peters A;
Wichmann HE;
George AL;
Roden DM
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A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de Pointes
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Sinner MF;
Porthan K;
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Havulinna AS;
Tikkanen J;
Müller-Nurasyid M;
Peloso G;
Ulivi S;
Beckmann BM;
Brockhaus AC;
Cooper RR;
Gasparini P;
Klopp N;
Meisinger C;
Peters A;
Thorand B;
Wichmann HE;
Salomaa V
(2012)
A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern
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Schurmann C;
Heim K;
Schillert A;
Blankenberg S;
Carstensen M;
Dörr M;
Endlich K;
Felix SB;
Gieger C;
Grallert H;
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Hoffmann W;
Homuth G;
Illig T;
Kruppa J;
Meitinger T;
Müller C;
Nauck M;
Peters A;
Strauch K;
Ziegler A
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Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium
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Quante AS;
Whittemore AS;
Shriver T;
Strauch K;
Terry MB
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Breast cancer risk assessment across the risk continuum: genetic and non-genetic risk factors contributing to differential model performance
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Taal HR;
St Pourcain B;
Thiering E;
Das S;
Mook-Kanamori DO;
Warrington NM;
Kaakinen M;
Kreiner-Moller E;
Bradfield JP;
Freathy RM;
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Guxens M;
Cousminer DL;
Klopp N;
Müller-Nurasyid M;
Tiesler C;
Wichmann HE;
Heinrich J;
Jaddoe VWV;
for the Early Growth Genetics (EGG) Consortium
(2012)
Common variants at 12q15 and 12q24 are associated with infant head circumference
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Grallert H;
Dupuis J;
Bis JC;
Dehghan A;
Barbalic M;
Baumert J;
Lu C;
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Uitterlinden AG;
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Khuseyinova N;
Schnabel RB;
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Rivadeneira F;
Hoogeveen RC;
Fontes JD;
Meisinger C;
Keaney JF;
Lemaitre R;
Gieger C;
Illig T;
Ballantyne CM
(2012)
Eight genetic loci associated with variation in lipoprotein-associated phospholiapase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies
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Petersen AK;
Stark K;
Musameh M;
Nelson C;
Römisch-Margl W;
Kremer W;
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Krug S;
Skurk T;
Rist M;
Hannelore D;
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Tomaszewski M;
Döring A;
Peters A;
Wichmann HE;
Kaess B;
Kalbitzer HR;
Illig T;
Gieger C;
Kastenmüller G
(2012)
Genetic associations with lipoprotein subfractions provide information on their biological nature
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Freilinger T;
Anttila V;
de Vries B;
Malik R;
Kallela M;
Terwindt GM;
Pozo-Rosich P;
Winswold B;
Nyholt DR;
van Oosterhout WPJ;
Artto V;
Todt U;
Hämäläinen E;
Fernández-Morales J;
Louter MA;
Kaunisto MA;
Schoenen J;
Raitakari O;
Lehtimäki T;
Vila-Pueyo M;
Göbel H;
Wichmann HE;
Sintas C;
Uitterlinden AG;
van den Maagdenberg AMJM;
for the International Headache Genetics Consortium
(2012)
Genome-wide association analysis identifies susceptibility loci for migraine without aura
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Amin N;
Byrne E;
Johnson J;
Chenevix-Trench G;
Walter S;
Nolte IM;
kConFab Investigators;
Vink JM;
Rawal R;
Mangino M;
Teumer A;
Keers JC;
Verwoert G;
Baumeister S;
Biffar R;
Petersmann A;
Dahmen N;
Döring A;
Isaacs A;
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Wray NR;
Montgomery GW;
Wichmann HE;
Martin NG;
van Duijn CM
(2012)
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM
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Huang J;
Sabater-Lleal M;
Asselbergs FW;
Tregouet D;
Shin SY;
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Baumert J;
Oudot-Mellkah T;
Folkersen L;
Johnson AD;
Smith NL;
Williams SM;
Ikram MA;
Kleber ME;
Becker DM;
Truong V;
Mychaleckyj JC;
Tang W;
Peters A;
Meisinger C;
Müller M;
DIAGRAM Consortium (with …Huth C, …);
Klopp N;
Hamsten A
(2012)
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation
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Demirkan A;
van Duijn CM;
Ugocsai P;
Isaacs A;
DIAGRAM Consortium (with Huth C, Grallert H, Gieger C, Klopp N, Petersen AK, Thorand B, Wichmann HE, Illig T, Meisinger C);
McCarthy MI
(2012)
Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations
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Boraska V;
Joroncic A;
Colonna V;
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Nyholt DR;
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Perry JRB;
Toniolo D;
Albrecht E;
Ang W;
Bandinelli S;
Barbalic M;
Barroso I;
Beckmann JS;
Biffar R;
Heid IM;
Klopp N;
Peters A;
Gieger C;
Wichmann HE;
Xue Y;
Zeggini E
(2012)
Genome-wide meta-analysis of common variant differences between men and women
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Ellinghaus E;
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Nair RP;
Debrus S;
Raelson JV;
Belouchi M;
Tejasvi T;
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Tsoi LC;
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Esko T;
Metspalu A;
Rahmann P;
Gladman DD;
Bowcock AM;
Helms C;
Krueger GG;
Koks S;
Kingo K;
Gieger C;
Wichmann HE;
Mrowietz U;
Weidinger S;
Weichenthal M;
Franke A
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Genome-Wide Meta-Analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL
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Becker A;
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Chenot JF;
Leonhardt C;
Keller S;
Baum E;
Pfingsten M;
Hildebrandt J;
Basler HD;
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Donner-Banzhoff N;
Strauch K
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Implementation of a Guideline for Low Back Pain Management in Primary Care
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Scott RA;
Lagou V;
Welch RP;
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Montasser ME;
Luan J;
Mägi R;
Strawbridge RJ;
Rehnberg E;
Gustafsson S;
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Rasmussen-Torvik LJ;
Yengo L;
Lecoeur C;
Shungin D;
Sanna S;
Sidore C;
Johnson PCD;
Jukema JW;
Gieger C;
Müller-Nurasyid M;
DIAGRAM Consortium;
Illig T;
Barroso I
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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
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Morris AP;
Voight BF;
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Strawbridge RJ;
Khan H;
Grallert H;
Mahajan A;
Prokopenko I;
Müller-Nurasyid M;
Meyer J;
Klopp N;
MAGIC Consortium;
Gieger C;
Peters A;
Illig T;
McCarthy MI;
for the DIAGRAM Consortium
(2012)
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
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Verhoeven VJM;
Hysi PG;
Saw SM;
Vitart V;
Mirshahi A;
Guggenheim JA;
Cotch MF;
Yamashiro K;
Baird PN;
Mackey DA;
Wojciechowski R;
Ikram MK;
Hewitt AW;
Duggal P;
Janmahasatian S;
Khor CC;
Fan Q;
Zhou X;
Young TL;
Tai ES;
Goh LK;
Li YJ;
Aung T;
Vithana E;
Döring A;
Klaver CCW
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Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium
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Jacobs DI;
Walsh KM;
Wrensch M;
Jenkins R;
Houlston RS;
Bondy M;
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Gousias K;
Schramm J;
Wichmann HE;
Müller-Nurasyid M;
Schreiber S;
Franke A;
Moebus S;
Eisele L;
DeWan A;
Dubrow R
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Leveraging Ethnic Group Incidence Variation to Investigate Genetic Susceptibility to Glioma: A Novel Candidate SNP Approach
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Okada Y;
Sim X;
Go MJ;
The CKDGen Consortium (with Köttgen A, …, Illig T, Klopp N, Meisinger C, Wichmann HE, …, Heid IM, Fox CS);
Albrecht E;
The GUGC consortium (with Köttgen A, …, Döring A, Lattka E, Strauch K, …, Gieger C);
Tanaka T
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Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations
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Ellinor PT;
Lunetta KL;
Müller-Nurasyid M;
Pfeufer A;
Sinner MF;
Steinbeck G;
Meitinger T;
Perz S;
Wichmann HE;
Kääb S
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Meta-analysis identifies six new susceptibility loci for atrial fibrillation
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Ellinor PT;
Lunetta KL;
Müller-Nurasyid M;
Pfeufer A;
Sinner MF;
Steinbeck G;
Meitinger T;
Perz S;
Wichmann HE;
Kääb S
(2012)
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
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Künzel T;
Strauch K
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Parameter Estimation and Quantitative Parametric Linkage Analysis with GENEHUNTER-QMOD
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Ried JS;
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Oexle K;
Meisinger C;
Winkelmann J;
Klopp N;
Meitinger T;
Peters A;
Suhre K;
Wichmann HE;
Gieger C
(2012)
PSEA: Phenotype Set Enrichment Analysis A New Method for Analysis of Multiple Phenotypes
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Perry JRB;
Voight BF;
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Amin N;
Dupuis J;
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Li M;
Qi L;
Steinthorsdottir V;
Scott RA;
Almgren P;
Arking DE;
Aulchenko Y;
Balkau B;
Bendiktsson R;
Bergman RN;
Boerwinkle E;
Gieger C;
Petersen AK;
Illig T;
Cauchi S
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Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases
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Viniol A;
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Brugger M;
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Baum E;
Becker A
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Study protocol: Transition from localized low back pain to chronic widespread pain in general practice: Identification of risk factors, preventive factors and key elements for treatment - A cohort study
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Hachulla E;
Cusi D;
Wichmann HE;
Müller-Nurasyid M;
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TGFß receptor gene variants in systemic sclerosis-related pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients
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Wilde AAM;
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Variants in the 3’ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner
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A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals
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A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3
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A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
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First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study
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Genetic Determinants of Serum Testosterone Concentrations in Men
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The International Multiple Sclerosis Genetics Consortium (IMSGC);
The Wellcome Trust Case Control Consortium 2 (WTCC2);
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Pirinen M;
Spencer CCA;
Patsopoulos NA;
Moutsianas L;
Dilthey A;
Su Z;
Freeman C;
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
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Genetic variants of the fatty acid desaturase gene cluster predict red blood cell docosahexaenoic and other polyunsaturated fatty acid levels in pregnant woman: findings from the Avon Longitudinal Study of Parents and Children
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Genetic variation in polyunsaturated fatty acid metabolism and its potential relevance for human development and health
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Genome-wide association analysis and fine mapping of NT-proBNP level provide novel Insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster
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Ryu E;
Hov JR;
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Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
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Liu Y;
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Genome-Wide Association Studies of the PR Interval in African Americans
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Erdmann J;
Willenborg C;
Nahrstaedt J;
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Gieger C;
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Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23
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Heier M;
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Gieger C;
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Wallaschofski H;
Meisinger C;
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(2011)
Genome-wide Association Study Identifies Four Genetic Loci Associated with Thyroid Volume and Goiter Risk
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Allanore Y;
Saad M;
Dieudé P;
Avouac J;
Distler JHW;
Amouyel P;
Matucci-Cerinic M;
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Airo P;
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Wichmann HE;
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Lambert JC;
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Genome-Wide Scan Identifies TNIP1, PSORS1C1, and RHOB As Novel Risk Loci for Systemic Sclerosis
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Schmitt J;
Chen CM;
Apfelbacher C;
Romanos M;
Lehmann I;
Herbarth O;
Schaaf B;
Kraemer U;
von Berg A;
Wichmann HE;
Heinrich J;
the LISA-plus Study Group
(2011)
Infant eczema, infant sleeping problems, and mental health at 10 years of age: the prospective birth cohort study LISAplus
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Schnabel RB;
Kerr KF;
Lubitz SA;
Alkylbekova EL;
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Mehra R;
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Mosley TH;
Mueller M;
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Wichmann HE;
Seshadri S;
Farlow DN;
Rotter JI;
Soliman EZ;
Heckbert SR;
for the Candidate Gene Association Resource (CARe)
(2011)
Large-Scale Candidate Gene Analysis in Whites and African-Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation: The NHLBI CARe Project
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Rzehak P;
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Reinhardt D;
von Berg A;
Krämer U;
Berdel D;
Bollrath C;
Grübl A;
Bauer CP;
Wichmann HE;
Heinrich J;
for the GINI-plus Study Group
(2011)
Long-term effects of hydrolyzed protein infant formulas on gowth – extended follow-up to 10 y of age: results from the German Infant Nutritional Intervention Study (GINI)
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Koch B;
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Vogelmeier CF;
Schnabel E;
Karrasch S;
Wichmann HE;
Schäfer T;
Schulz H;
Heinrich J;
Gläser S
(2011)
Lung function reference values in different German populations
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Bis JC;
Kavousi M;
Franceschini N;
Isaacs A;
Abecasis GR;
Schminke U;
Post W;
Smith AV;
Cupples LA;
Markus HS;
Schmidt R;
Huffman JE;
Lehtimäki T;
Baumert J;
Münzel T;
Heckbert SR;
Meisinger C;
Wichmann HE;
Illig T;
Klopp N;
O'Donnell CJ
(2011)
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque
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Paternoster L;
Standl M;
Chen CM;
Ramasamy A;
Bonneglykke K;
Duijts L;
Ferreira MA;
Cuoto Alves A;
Thyssen JP;
Albrecht E;
Wichmann HE;
Müller-Nurasyid M;
Klopp N;
Tiesler CMT;
Thiering E;
Illig T;
Gieger C;
Heinrich J;
Weidinger S
(2011)
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
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Jacquemont S;
Reymond A;
Zufferey F;
Harewood L;
Walters RG;
Kutalik Z;
Martinet D;
Shen Y;
Valsesia;
Beckmann ND;
Thorleifsson G;
Belfiore M;
Bouquillon S;
Campion D;
de Leeuw N;
de Vries BBA;
Esko T;
Fernandez BA;
Fernandez-Aranda F;
Fernandez-Real JM;
Gratacos M;
Guilmatre A;
Hoyer J;
Jarvelin MR;
Gieger C;
Beckmann JS;
Froguel P
(2011)
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus
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Nalls MA;
Couper DJ;
Tanaka T;
van Rooij FJA;
Chen MH;
Smith AV;
Toniolo D;
Zakai NA;
Yang Q;
Greinacher A;
Wood A;
Garcia M;
Gasparini P;
Liu Y;
Lumley T;
Folsom AR;
Reiner AP;
Gieger C;
Döring A;
Illig T;
Kühnel B;
Wichmann HE;
Ganesh SK
(2011)
Multiple Loci Are Associated with White Blood Cell Phenotypes
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Sibbing D;
Pfeufer A;
Perisic T;
Mannes AM;
Fritz-Wolf K;
Unwin S;
Sinner MF;
Gieger C;
Gloeckner CJ;
Wichmann HE;
Kremmer E;
Schäfer Z;
Walch A;
Hinterseer M;
Näbauer M;
Kääb S;
Kastrati A;
Schömig A;
Meitinger T;
Bornkamm GW;
Conrad M;
von Beckerath N
(2011)
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy
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Oexle K;
Ried JS;
Hicks AA;
Tanaka T;
Hayward C;
Bruegel M;
Gögele M;
Lichtner P;
Müller-Myhsok B;
Döring A;
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Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels
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Kilpeläinen TO;
Qi L;
Brage S;
Sharp SJ;
Sonestedt E;
Demerath E;
Ahmad T;
Mora S;
Kaakinen M;
Sandholt CH;
Holzapfel C;
Autenrieth C;
Hyppönen E;
Cauchi S;
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Kutalik Z;
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Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218, 166 Adults and 19, 268 Children
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Herder C;
Peeters W;
Illig T;
Baumert J;
de Kleijn DPV;
Moll FL;
Poschen U;
Klopp N;
Müller-Nurasyid M;
Roden M;
Preuss M;
CARDIoGRAM Consortium;
Karakas M;
Meisinger C;
Thorand B;
Pasterkamp G;
Koenig W
(2011)
RANTES/ CCL5 and Risk for Coronary Events: Results from the MONICA/KORA Augsburg Case-Cohort, Athero-Express and CARDIoGRAM Studies
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Breitfelder A;
Wenig CM;
Wolfenstetter SB;
Rzehak P;
Menn P;
John J;
Leidl R;
Bauer CP;
Koletzko S;
Röder S;
Herbarth O;
von Berg A;
Berdel D;
Kraemer U;
Schaaf B;
Wichmann HE;
Heinrich J;
the GINI-plus and LISA-plus Study Groups
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Relative weight-related costs of healthcare use by children – Results from the two German birth cohorts, GINI-plus and LISA-plus
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Dolmans G;
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Becker K;
van der Vlies P;
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Nothnagel M;
Franke A;
Klopp N;
Wichmann HE;
Nürnberg P;
Giele H;
Ophoff R;
Wijmenga C;
for the Dutch Dupuytren Study Group;
for the German Dupuytren Study Group;
for the LifeLines Cohort Study;
for the BSSH-GODD Consortium
(2011)
Wnt Signaling and Dupuytren`s Disease
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